State of Health Podcast #10: Wim Hof Method Impact on Nervous System & Immune Response to Endotoxin

On this episode of the podcast, I go over the methods, results and conclusions of a study to test the Wim Hof Method. Who is Wim Hof and what is his method? Wim Hof is a Dutch extreme athlete who has broken several crazy world records such as longest time in direct, full-body contact with ice or farthest swim under ice earning himself the nickname of The Iceman. Wim claims that his feats of extreme endurance are not something unique to him but rather something that can be developed by anyone over time using his method. The Wim Hof method consists of 3 components: meditation, cold exposure and breathing techniques.

In the study, Wim taught and trained his three-part method to study participants for less than a week and they had approximately an additional week to practice on their own, after which they were tested by getting injected with endotoxin.

What is endotoxin? It is a molecule from bacteria which when injected has been shown to cause the subject to experience fever-like symptoms as the body’s innate immune system responds. That is everybody except Wim Hof, he had reduced symptoms and a difference in his immune response. So the question is: Could other people trained by Wim also be able to have a different response to getting injected by endotoxin after learning and training the Wim Hof Method for a short period of time?

So if all that sounds interesting then this podcast episode is for you.

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Time codes

0:15 - Intro

2:33 - Start of episode

3:36 - Wim Hof World Records

6:15 - What is the Sympathetic Nervous System?

8:18 - What is the Innate Immune Response?

10:37 - General Experiment Introduction

16:42 - Materials and Methods of Experiment

26:44 - What are Cytokines?

28:18 - Results of Experiment

40:17 - Summary and Discussion

51:47 - My Final Thoughts

55:50 - Outro

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