The Proof with Simon Hill

Episode #345. Don’t take your eyesight for granted. Join me as I sit down with optometrist Dr Joseph Allen to discover science-backed ways to care for your eyes, including common eye health myths, practical strategies for protecting your vision, and expert advice on maintaining healthy eyes for life. Learn how diet and lifestyle affect your eyesight, the truth about blue light glasses, and why regular eye exams are essential. Dr Allen also shares tips on contact lens safety, myopia prevention, and keeping your eyes healthy for years to come. Specifically, we discuss:  Introduction to Eye Health and Dr. Joseph Allen's Expertise (00:00) Dr Allen’s Journey: From Thick Glasses to Optometry Career (02:18) Busting Eye Health Myths and Misconceptions (06:25) How the Human Eye Works: Vision Explained (08:39) Top Eye Conditions: Causes, Symptoms, and Treatments (11:04) The Myopia Epidemic: Causes and Solutions (19:50) Best Practices for Maintaining Optimal Eye Health (25:12) Do Blue Light Blocking Glasses Work? A Scientific Look (33:30) The Role of Diet in Eye Health: What to Eat for Better Vision (39:52) Omega-3 Fatty Acids and Their Impact on Eye Health (46:54) Key Nutrients for Vision: Lutein, Zeaxanthin, and Leafy Greens (01:04:40) Essential Vitamins and Nutrients for Long-Term Eye Health (01:14:10) The Truth About Eye Exercises: Myths and Realities (01:21:17) Contact Lenses: Risks, Benefits, and Best Practices (01:29:16) Vision Correction Surgery: Future Trends and Options (01:33:49) Age-Related Vision Challenges: Managing Presbyopia and More (01:38:53) Expert Tips and Final Recommendations for Lifelong Eye Health (01:44:42) Learn more from Dr Joseph Allen on YouTube, and connect with him on Instagram, Facebook, or Twitter/X. This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link for 20% off one-time purchases and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Pique Tea Pique's Nandaka provides sustainable, all-day energy and makes you feel like you’re doing something good for your body! Try Pique and get up to 20% off plus a FREE rechargeable frother and glass beaker when you purchase exclusively at piquelife.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Episode #344. Creatine isn’t just for athletes – it’s a powerhouse supplement that benefits people of all ages and activity levels. Join me to unpack the science behind creatine and explore five evidence-based reasons why it could play a vital role in improving your health and performance. You’ll learn how creatine supports muscle strength, endurance, brain function, and even bone health. I’ll also break down dosing guidelines, clear up common misconceptions, and explore how this safe, well-studied supplement could be a game-changer for your health and performance. Specifically, we discuss: Introduction to Creatine: The Supplement Everyone Should Consider (00:00) What is Creatine? Basics, Benefits, and Origins Explained (00:56) Strength & Muscle Mass: How Creatine Amplifies Gains (03:22) Endurance & Recovery: Boost Performance with Creatine (09:24) Osteoarthritis Relief: Creatine for Joint Health and Mobility (12:56) Brain Health & Cognition: How Creatine Enhances Mental Performance (15:29) Bone Health: Strengthen Your Bones with Creatine (22:23) Choosing the Best Creatine: Types, Quality, and Recommendations (24:25) Creatine Dosage: How Much to Take for Optimal Results (28:31) Conclusion: Unlock the Full Potential of Creatine (31:08) This episode is brought to you by: 38TERA Consider 38TERA's DMN prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link for 20% off one-time purchases and subscriptions. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Episode #343. Vegan vs. carnivore – which diet stands up to the science? Join me in this fiery debate to find out. Hosted by Ellen Fisher, this thought-provoking episode pits me, Simon Hill, against Dr Robert Kiltz, a leading voice in the carnivore and keto movements. Together, we explore opposing perspectives on nutrition, from the hierarchy of evidence to the health implications of plant-based and animal-based diets. Whether you’re vegan, carnivore, or somewhere in between, this conversation will challenge your views and help you make more informed decisions about your health and the planet. Specifically, we discuss: Introduction (00:00) Personal Health Journeys: How Diet Shapes Our Lives (02:20) Scientific Evidence vs. Personal Anecdotes: Finding the Truth (07:50) Nutritional Science and Its Impact on Public Health (16:51) Mechanisms and Metabolic Health (22:55) Why Experts Disagree: Conflicting Views on Diet and Health (30:16) Ansel Keys Revisited: The Fat vs. Sugar Debate in Nutrition (54:45) Outliers in Research: How They Influence Diet Discussions (55:55) Did Humans Evolve to Eat Meat or Plants? (57:36) The Role of Fat: Separating Myths from Scientific Evidence (59:23) How Funding Influences Scientific Studies and Nutrition Advice (01:08:57) Why Dietary Guidelines Are So Complex and Confusing (01:13:17) Plant-Based vs. Carnivore: Which Diet Is Healthier? (01:18:58) Anecdotes in Nutrition: Do Personal Stories Hold Weight? (01:26:16) Diverse Perspectives: Why They Matter in Nutrition Science (01:30:44) Is There an Objective Truth in Nutrition Science? (01:46:01) Diet and Individual Truths: Why One Size Doesn’t Fit All (01:46:27) Profit Motives in Science and Medicine: What’s the Impact? (01:48:22) Processed Foods: Their Role in the Decline of Public Health (01:50:18) Health Testing: Can We Trust the Results? (01:53:03) Balancing Diet and Nutritional Freedom: Finding What Works (01:54:14) The Power of Stories: How They Shape Our Nutrition Beliefs (01:57:24) Evolutionary Diets: Do They Hold the Key to Health? (02:13:07) Ethical Diets and Planetary Health: Making Sustainable Choices (02:29:42) Final Reflections: Key Insights from the Nutrition Debate (02:33:36) Discover more of The Ellen Fisher Podcast at https://www.ellenfisher.com/podcast. Learn more about Dr Kiltz at https://www.doctorkiltz.com/blog/. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 20% off your first order and subscriptions. NordVPN Protect your personal data and browse with confidence using NordVPN. With fast servers and advanced encryption, NordVPN protects you – even on public Wi-Fi – and unlocks content worldwide. EXCLUSIVE NordVPN Deal ➼ nordvpn.com/theproof. Try it risk-free with a 30-day money-back guarantee. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify

Episode #342. My all-in-one guide to nutrition: learn how to eat for health, performance, and the planet. In this special episode, I’m interviewed by Kristen Holmes, VP of Performance Science at WHOOP, for a conversation about the principles of plant-based eating and how our food choices influence long-term health and recovery. You’ll learn about the key principles of a healthy diet, the truth about protein and legumes, and the environmental impact of what’s on your plate. We also explore fascinating WHOOP data on how diet affects sleep and recovery, making this episode essential listening for anyone looking to optimise their health, performance, and wellness through nutrition. Specifically, we cover: My perspective on plant-based nutrition (00:00) Key principles of a healthy diet and debunking myths (03:29) Exploring Scientific Evidence Supporting Plant-Based Diets (13:01) How to transition to healthier dietary patterns (19:10) The truth about legumes and their nutritional value (24:17) Nutrition and protein sources in plant-based diets (31:00) Insights on sleep, recovery, and diet from Whoop data (41:16) The impact of food choices on the environment (50:24) Final thoughts and additional resources (57:03) This episode is brought to you by: 38TERA During Black Friday week get 20% off 38TERA's complete prebiotic DMN. Formulated by Dr Will Bulsiewicz and myself, DMN is the perfect way to conveniently take your gut health to the next level. Discount automatically applied at checkout at 38tera.com. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to [Eimele.com](https://eimele.com/essential-8/15660280.html.) and use code SIMON at checkout for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT LMNT’s Chocolate Medley is back. A variety pack of choc mint, choc chai, and choc raspberry electrolytes for proper hydration. Stay hydrated with LMNT. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high-protein Plant Performance recipe book

Episode #341. Confused about oils, butter, and fats in your diet? This masterclass explores which fats to prioritise, which to avoid, and how different types of fats influence your health. This episode features both a solo deep dive into the science of fats and expert contributions from past guests, offering practical tips and evidence-based guidance for smarter food choices. Joining me in this episode are world-class experts, including Dr Philip Calder, Dr Gary Fraser, Dr Gil Carvalho, Prof Roy Taylor, Dr Alan Flanagan, Dr Matthew Nagra, Dr Walter Willett, Dr Ayesha Sherzai, and Dr Dean Sherzai. Together, we unpack the science behind dietary fats and provide evidence-based insights to guide your long-term health decisions. Specifically, we discuss: Introduction (00:00) Understanding Dietary Fats: Saturated, Unsaturated, and Trans Fats (00:48) Essential vs. Non-Essential Fats (05:47) Omega-3 and Omega-6 Fatty Acids: Benefits and Sources (06:31) Brain Health and Omega-3s (07:48) Saturated vs. Unsaturated Fats and Cardiovascular Health (16:41) The Role of Omega-6 Fats in Inflammation (48:26) Insulin Resistance and Liver Fat (01:08:48) The Twin Cycle Hypothesis (01:11:04) Saturated vs. Unsaturated Fats and Fatty Liver (01:21:21) Canola Oil and Health (01:38:37) Dairy Fats and Cardiovascular Health (01:55:26) Optimising Fats in Your Diet (02:04:03) Conclusion and Recommendations (02:07:59) Head to the full show notes for additional resources and to connect with today’s guests. This episode is brought to you by: 38TERA During Black Friday week get 20% off 38TERA's complete prebiotic DMN. Formulated by Dr Will Bulsiewicz and myself, DMN is the perfect way to conveniently take your gut health to the next level. Discount automatically applied at checkout at 38tera.com. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Pique Tea Pique has unveiled its most exclusive Black Friday Cyber Monday offer ever! Get free exclusive gifts with link: piquelife.com/simon. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Episode #340. Think metabolic health is all about carbs and calories? You might be missing a crucial part of the puzzle. Join me as I break down how the location and type of fat your body stores can dramatically impact your health and risk of disease. In this episode, you'll learn how body fat distribution influences your risk of metabolic disease, why weight impacts individuals differently, and how to determine if you have excess fat in your liver. Plus, discover my 6 key tips for enhancing your metabolic health through diet, exercise, and lifestyle adjustments. Specifically, we discuss: 00:00 What Is Metabolic Health and Why It Matters 00:41 The Root Cause of Poor Metabolic Health Revealed 02:55 Understanding Your Personal Fat Threshold (Key to Fat Loss) 04:32 The Twin Cycle Hypothesis: How Fat Affects Metabolism 05:10 Liver Fat: The Hidden Culprit of Metabolic Disorders 16:16 6 Proven Strategies to Reduce Ectopic & Visceral Fat 33:36 Key Takeaways: Fixing Metabolic Health in 6 Steps 35:00 Bonus Discover more insights and supporting studies in the full show notes. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Follow this link to Eimele's website for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code LIVINGPROOF at checkout for 25% off and receive a free gift of 5 nights of their best-selling Sleep packs for orders over $75 at livemomentous.com. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF to get up to $600 off your Pod 4 Ultra purchase when bundled at eightsleep.com/theproof. This is their highest offer of the year! Try it risk-free for 30 days, with worldwide shipping. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 25% off all mattresses and 2 free pillows at birchliving.com/simonhill. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Episode #339. Are you getting the full picture of your heart health? Learn why ApoB is the test you shouldn't skip. In this episode, I sit down with Dr Daniel Soffer, a preventive cardiologist and lipidologist, to break down the importance of ApoB testing for cardiovascular risk assessment. You'll learn why ApoB provides more comprehensive insights than LDL cholesterol alone, who can benefit most from this test, and how it fits into preventive cardiology. Dr Soffer shares practical advice for assessing cardiovascular disease risk, discusses the implications of diet and genetics on heart health, and explores case studies to help you understand when and why ApoB testing is crucial. Specifically, we discuss:  Introduction (00:00) Insight into Preventive Cardiology and Lipidology (01:38) Understanding Lipoproteins and Their Role in Cardiovascular Disease (06:40) Techniques for Lipoprotein Testing and Measurement (11:33) Exploring Atherosclerosis and Lipoprotein Retention Hypothesis (31:18) Epidemiological Changes in Health and Cardiovascular Profiles (55:06) Concerns about the Keto Diet and Elevated ApoB Levels (58:26) Approaches to Managing Elevated LDL Levels Clinically (01:01:13) The Role of Evidence-Based Medicine in Cardiovascular Guidelines (01:07:15) Comparing ApoB and LDL Cholesterol in Cardiovascular Risk (01:14:36) Understanding Discordance in Lipid Measurements (01:18:36) Advanced Imaging Techniques for Risk Assessment (01:25:50) Guidelines and Considerations for Statin Therapy (01:44:30) Coronary Artery Calcium Score, Stroke Risks, and Carotid Ultrasound (01:54:03) Dietary Interventions and Carotid Intima-Media Thickness (IMT) (01:59:22) Case Study: Family History’s Role in Cardiovascular Risk (02:05:05) Overview of Statins, PCSK9 Inhibitors, and Other Lipid-Lowering Therapies (02:12:24) Aspirin Therapy and Imaging in Cardiovascular Health (02:26:06) Setting Treatment Thresholds Based on ApoB Levels (02:39:57) Closing Thoughts on Cardiovascular Risk and ApoB (02:44:16) This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Use code LIVINGPROOF at checkout for 25% off and receive a free gift of 5 nights of their best-selling Sleep packs for orders over $75 at at livemomentous.com. Pique Tea Pique’s Black Friday special is HERE. For a limited time, get a Chai tea FREE with your qualifying purchase at piquelife.com/simon. This is the only time you can get your hands on their Chai. Act fast; this limited-time offering is sure to sell out! The offer ends November 16th. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF to get up to $600 off your Pod 4 Ultra purchase when bundled at eightsleep.com/theproof. This is their highest offer of the year! Try it risk-free for 30 days, with worldwide shipping. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook

Episode #338. Struggling with acne, aging, or other skin concerns? Discover how to build a science-backed skincare routine with insights from Carter “Eviba” Gottlieb. In this episode, I’m joined by Carter and special guest Tawny Janae to explore the essentials of skincare, breaking down what truly works and what might be a waste of time and money. You’ll learn about foundational skincare steps, the benefits of active ingredients like retinoids and niacinamide, and how to protect your skin from sun damage. Carter also shares tips for managing acne, avoiding common skincare myths, and building a routine that supports long-term skin health. If you’re looking to enhance your skin’s appearance and health, this episode is packed with practical, evidence-based advice. Specifically, we discuss: Introduction: Unveiling the Science of Skin Care (00:00) Carter’s Path into Dermatology and Science-Based Skincare (04:35) Carotenoids and Their Effects on Skin Health and Appearance (08:58) Debunking Myths About Supplements and Skincare (17:31) Essentials of Skin Care: Slugging, Moisturizers, and More (29:03) Retinoids Explained: Anti-Aging Powerhouses (37:31) How Exercise and Hydration Affect Skin Health (52:41) Tips for Choosing the Right Moisturizer (53:40) Understanding Skin Pigmentation and Anti-Ageing (56:38) Why Sunscreen Is the Ultimate Skin Protector (01:07:32) How to Choose the Best Sunscreen for Your Skin (01:17:58) Do Skincare Devices Really Work? (01:37:30) Gua Sha and the Benefits of Facial Massages (01:45:04) The Truth About Facials and Chemical Treatments (01:47:23) Effective Acne Treatments: Science-Backed Solutions (01:56:02) Pimple Popping: What You Should and Shouldn't Do (02:05:36) Final Thoughts on Skincare (02:14:05) Connect with Carter Gottlieb on TikTok, Instagram, YouTube, or at evibacarter.com. Connect with Tawny Janae on Instagram or YouTube, and discover 300+ classes on Alo Moves. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT Stay hydrated with LMNT – a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 20% off all mattresses and 2 free pillows at birchliving.com/simonhill. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify

Episode #337. An estimated 45% of dementia cases are preventable – find out how you can reduce your risk by targeting these 14 modifiable factors. Today I’m joined by Dr Kellyann Niotis, the first fellowship-trained preventive neurologist, to explore the latest research on dementia prevention and how simple lifestyle changes can dramatically reduce your risk. In this episode, we break down The Lancet’s 14 modifiable risk factors for dementia, from managing LDL cholesterol and staying physically active to addressing hearing loss and improving your mental health. You’ll also learn about the links between nutrition, sleep, and brain health, and why it’s never too early – or too late – to start taking care of your brain. Specifically, we discuss: Introduction (00:00) Pioneering Preventive Neurology (00:07) Decoding Neurodegenerative Diseases (00:56) Understanding the Phases of Neurodegeneration (02:09) Early Indicators: Preclinical Signs and Cognitive Impairment (07:12) Uncovering Dementia’s Risk Factors and Preventive Steps (11:33) How Education Builds Cognitive Reserve Against Dementia (22:37) Why Vision and Hearing Loss Could Raise Dementia Risk (27:45) The Link Between Oral Health and Cognitive Decline (40:45) How Depression Influences Dementia Risk (52:33) Head Trauma’s Impact on Cognitive Health (59:21) How Head Injuries May Contribute to Dementia (01:01:35) How Exercise Benefits Brain Health and Longevity (01:11:43) Social Connections: A Key to Cognitive Health (01:23:56) How Diabetes Increases Dementia Risk (01:30:03) Hypertension’s Role in Cognitive Decline (01:48:00) Optimal Blood Pressure Goals for Brain Health (01:59:08) Alcohol’s Effects on Brain Function (02:01:12) Recreational Drugs and Brain Degeneration (02:09:38) Smoking’s Effect on Dementia Risk (02:12:00) The Link Between Air Pollution and Cognitive Health (02:17:49) Environmental Toxins and Dementia Risk (02:22:35) Diet Choices That May Help Prevent Dementia (02:29:30) Why Quality Sleep is Essential for Brain Health (02:35:44) Menopause’s Influence on Dementia Risk (02:46:26) Closing Thoughts and Contact Information (02:52:28) Connect with Dr Kellyann Niotis on Instagram, LinkedIn, and via her website, https://drkellyannniotis.com/. Listen to her appearance in Episode #333 here. Head to the full show notes for additional insights and supporting studies. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Pique Tea Stay energised without the coffee crash with Pique’s Sun Goddess Matcha. Organic, ceremonial-grade, and uniquely loaded with l-theanine to keep you calm and focused. Get up to 15% off plus a free beaker and frother at piquelife.com/simon. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping.

Episode #336. What if our food systems could help heal the Earth? Join me as I sit down with ethnobotanist Stephen Brooks to explore permaculture, alternative living, and the future of agriculture. Together, we discuss how you can be part of the solution to building a better balance between humans and nature. You’ll learn about the principles of permaculture, the ethical issues in modern food systems, and some unique fruits to seek out. Stephen also shares his vision for designing cities and agriculture that work in harmony with the planet, and why now is the time to get involved in the transition to a healthier world. Specifically, we discuss: The World of Fruit and Plants: Connection to Nature (00:00) From Miami to Costa Rica: A Journey into Sustainability (03:59) Environmental Injustice and the Impact on Communities (05:08) Permaculture and Sustainable Agriculture Practices (11:54) How to Build Sustainable Communities through Permaculture (26:30) Perennial Vegetables: A Key to Sustainable Agriculture (39:15) Diet Trends, Agriculture, and Sustainable Living Practices (41:56) Sustainable Human Systems: Permaculture and Design (48:59) Renewable Energy Solutions for Sustainable Communities (01:16:32) Practical Urban Farming and Sustainable Practices (01:19:55) The Joy of Nitrogen-Fixing Plants and Sustainable Farming (01:30:36) Fruit Ceremonies: Building Community and Connection (01:38:30) Blueprint for Sustainable Living and Community Building (01:44:30) Connect with Stephen on Instagram, where you can find more information about his current and upcoming projects. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 20% off all mattresses and 2 free pillows at birchliving.com/simonhill. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants

Episode #335. Struggling to keep weight off long term? Learn the science behind successful fat loss and maintenance with experts Kevin Maki, PhD, and Carol Kirkpatrick, PhD. In this episode, we discuss evidence-based strategies for losing body fat and keeping it off, while exploring the role of nutrition, exercise, and pharmacological interventions. You’ll learn about the impact of protein and fibre on hunger and satiety, the benefits of regular exercise for insulin sensitivity, and the potential role of medications like GLP-1 agonists. Dr Maki and Dr Kirkpatrick also share insights on the challenges of maintaining weight loss and how to make lasting changes for better health. Specifically, we discuss: Introductions (00:00) Carol’s Journey into Nutrition and Research Development (04:27) Kevin’s Path in Cardiometabolic Health Research (11:53) The Importance of Observational Studies in Nutrition (14:59) Understanding Dietary Fats and Cardiometabolic Health (19:49) Public Health Nutrition: Current Challenges and Opportunities (31:55) Exploring Obesity and Its Impact on Metabolic Health (43:19) How Exercise Enhances Insulin Sensitivity (53:35) The Link Between Insulin Resistance and Ectopic Fat (55:01) Weight Loss Challenges: Why It’s So Hard to Keep the Weight Off (01:01:05) How GLP-1 Agonists Are Transforming Obesity Treatment (01:04:02) Behavioural Aspects of Obesity: Understanding the Psychology (01:11:22) The 30-30-30 Study: A New Approach to Sustainable Weight Loss (01:24:44) Cholesterol, Fibre, and Cardiovascular Health (01:44:02) Protein Supplements and How They Affect Digestion (01:46:56) Dietary Patterns and Regulating Appetite for Better Health (01:49:23) Exploring the 30-30-30 Framework for Weight Loss (01:51:49) How Protein Sources Influence Metabolic Health (01:57:53) Carbohydrate Quality vs. Restriction: What Matters More? (02:14:57) Exercise for Weight Maintenance and Long-term Health (02:27:12) The Future of Nutrition Research and Public Health (02:30:25) Final Thoughts (02:35:10) Connect with Kevin Maki, PhD on LinkedIn and at https://www.mbclinicalresearch.com/. Connect with Carol Kirkpatrick, PhD on Twitter/X and LinkedIn. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 20% off your first order and subscriptions. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 20% off your first purchase by using the code LIVINGPROOF at checkout at livemomentous.com Pique Tea Stay energised without the coffee crash with Pique’s Sun Goddess Matcha. Organic, ceremonial-grade, and uniquely loaded with l-theanine to keep you calm and focused. Get up to 15% off plus a free beaker and frother at piquelife.com/simon. Eight Sleep Upgrade your sleep with the Pod 4 Ultra by Eight Sleep. Clinically validated to deliver up to 1 extra hour of quality sleep per night through temperature control and biometric tracking. Use code THEPROOF for $350 off at eightsleep.com/theproof. Try it risk-free for 30 days, with worldwide shipping. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Episode #334. Can we turn back the clock on our biology? Join me as I sit down with Nobel Prize-winning structural biologist Dr Venki Ramakrishnan to discuss why we age, how we age, and the scientific advancements helping us live longer and healthier lives. In this episode, you'll learn about the core reasons behind aging, the role of ribosomes and DNA damage in this process, and the science behind popular longevity interventions. Dr Ramakrishnan shares his insights on misleading anti-aging claims, how much control we truly have over aging, and the truth about "biological age". We also explore practical ways to slow down aging and extend our healthspan. Specifically, we discuss: Introduction to Aging and Longevity Science (00:00) Ribosomes and Their Role in Longevity Research (00:57) Controversies in Anti-Aging Research (05:09) Understanding the Biology of Aging (11:25) Genetics and Evolution: How They Shape Human Lifespan (22:10) Youthful Cells: The Future of Longevity Studies (29:38) Biological Interventions in Aging: Potential and Risks (46:09) Ancestral Living and Traditional Medicine for Longevity (52:09) Cellular Aging Mechanisms: A Deeper Look (56:51) Protein Synthesis and Its Impact on Aging Processes (01:04:19) DNA Damage and Repair: Implications for Aging (01:16:53) Lifestyle Choices That Influence Aging and Lifespan (01:24:03) Philosophical Perspectives on Extended Human Longevity (01:32:53) Concluding Thoughts on Aging and Longevity Research (01:43:21) Learn more about Dr Venki Ramakrishnan here, and be sure to check out his books Gene Machine and Why We Die. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 20% off your first order and subscriptions. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Episode #333. What does cholesterol have to do with dementia? Learn how to protect your brain health in the long term with this information you should be considering from your twenties and thirties. From cutting-edge science on cholesterol metabolism to fourteen key risk factors for dementia, we break down what you can do now to reduce your risk of cognitive decline later. In this episode, I’m joined by two renowned experts, Dr Kellyann Niotis and Dr Thomas Dayspring. Together, we explore the connection between cholesterol and dementia, personalised prevention strategies, and how making lifestyle changes today can safeguard your brain for the future. Specifically, we discuss: Intro (00:00) Cardiology Meets Neurology: Understanding the Connection (07:53) Dementia and Neurodegenerative Diseases: A Comprehensive Overview (13:26) Recognizing Early Dementia Signs and Risk Factors (21:43) Lipoproteins and Brain Health: The Crucial Link (32:36) ApoB vs ApoE: Comparing Apoprotein Functions in Neurological Health (44:24) APOE4 Carriers: Potential Therapeutic Approaches (01:00:30) ApoA1 and HDL: Their Role in Dementia Prevention (01:03:27) Genetic Testing for Dementia: Understanding APOE4 Implications (01:13:19) APOE4 Gene: Impact on Dementia Risk and Brain Health (01:17:58) Desmosterol's Role in Maintaining Brain Health (01:20:56) LDL Cholesterol: A Key Factor in Dementia Risk Assessment (01:34:05) APOE4: Comparing Single vs. Double Copy Risk Factors (01:39:15) Omega-3 Fatty Acids: Essential Nutrients for Brain Health (01:38:49) LDL Cholesterol Levels: Assessing Low vs. High Risk for Dementia (01:56:50) Key Takeaways: Preventive Neurology and Future Research Directions (02:00:10) Connect with Dr Kellyann Niotis at https://drkellyannniotis.com/ and discover research and resources at https://ind.org/. Connect with Dr Thomas Dayspring on Twitter/X or LinkedIn, and listen to his past appearances on The Proof here. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Birch Sleep deeply and wake up refreshed with a Birch Natural Mattress, combining premium natural materials with unbeatable comfort. Rest easy with a 100-night trial and 25-year warranty. Get 25% off all mattresses and 2 free pillows at birchliving.com/simonhill. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants

Episode #332. Blood tests can be confusing, but they don’t have to be. Learn how to interpret your comprehensive blood test results as I walk through key markers for cardiometabolic, hormonal, and overall health. Discover why I recommend blood tests every 6–12 months, learn the results of my most recent blood test, and hear insights from esteemed scientists Dr Thomas Dayspring and Dr Karl Nadolsky in this thorough guide. Specifically, I cover: Introduction (00:00) Personal Health Journey and Lifestyle Context (04:06) Cardiometabolic Biomarkers: Cholesterol, Triglycerides, and ApoB (09:29) Debunking the Triglycerides-to-HDL Ratio Debate (20:56) Insulin Sensitivity and Metabolic Health Markers (29:10) Hormones: Testosterone Levels and Testing (30:42) Thyroid Function: Family History and Test Interpretation (37:19) Iron and Micronutrient Insights (50:12) Key Lifestyle Habits for Optimal Health and Final Thoughts (51:44) Download my full blood test results here, or head to the full show notes for additional resources and supporting studies. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com. Pique Tea Stay energised without the coffee crash with Pique’s Sun Goddess Matcha. Organic, ceremonial-grade, and uniquely loaded with l-theanine to keep you calm and focused. Get up to 15% off plus a free beaker and frother at piquelife.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Episode #331. Are you getting the right balance of omega-3 and omega-6 fats in your diet? Join me as I sit down with leading scientists to explore the role these essential fatty acids play in your health. From brain development and cognitive function to heart health and inflammation, we unpack how these fats impact your well-being and address common misconceptions about omega-6 fats. You’ll hear from top voices in nutrition, including Dr Bill Harris, Dr Joel Fuhrman, Dr Ayesha Sherzai, Dr Dean Sherzai, Dr Gary Fraser, Dr Phillip Calder, and Dr Kristina Harris. Each expert shares valuable insights into how omega-3s and omega-6s influence everything from cognitive function to heart disease. We cover: Introduction to Omega-3 and Omega-6 Fatty Acids (00:00) What is Omega-6 and Why the Body Needs It (01:06) What is Omega-3 and Do We Really Need It? (12:29) The Importance of Optimising Omega-3 Consumption (42:50) Understanding DHA and EPA: Why Are They Essential? (50:01) Are Omega-3s the Most Important Fatty Acids for Brain Health? (55:44) APOE4 and Omega-3 Supplementation: What You Need to Know (1:08:50) Low Omega-3 Index and Neurological Problems in Seventh-day Adventist Church Members (1:15:00) Omega-3 Supplementation vs Fatty Fish: What Does Research Indicate? (1:21:53) Understanding Essential Fats: Benefits and Sources (1:27:25) Low Conversion Rates: From ALA to EPA & DHA Explained (1:31:39) The Importance of Monitoring Omega-6 Intake (1:37:03) The Link Between Omega-6 Fatty Acids and Inflammation (1:40:55) Major Omega-6 Food Sources and Healthier Alternatives (1:45:45) Balancing Omega-3 & Omega-6 to Reduce Inflammation (1:50:25) The Health Implications of Replacing Saturated Fat with Linoleic Acid (1:53:48) Polyunsaturated Fats and Cardiometabolic Health (1:58:19) How Omega-3 & Omega-6 Influence Insulin Resistance and Blood Pressure (2:01:44) The Long-Term Impact of Consuming Polyunsaturated Fats (2:06:32) Why You Should Measure Your Omega-3 Levels (2:10:07) DHA and EPA: Food Sources and Effective Supplementation (2:14:20) What Forms of DHA and EPA Supplementation Are Most Effective? (2:18:37) How to Properly Store DHA and EPA Supplements (2:20:27) Pregnancy and Omega-3s: Essential Benefits (2:21:33) Supplementing Omega-3s During Pregnancy: Guidelines (2:29:55) Omega-3 Supplementation Protocol: A Comprehensive Guide (2:38:16) Outro (2:52:15) Thank you for tuning in, and for your ongoing commitment to your health. If you found this episode helpful, please share it with someone who could benefit from it. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants

Episode #330. Uncover the key foundations of a healthy diet and learn how to reduce your risk of chronic disease. What does it take to truly eat well? How do you stay healthy in a food system that prioritises profit? In this episode, originally recorded for Sigma Nutrition Radio, I answer these questions and more. Learn practical, science-based strategies for building healthier eating habits that can have a lasting impact on your well-being. Tune in to explore topics like nutrition, chronic disease prevention, and how to make informed dietary choices for better long-term health. Specifically, we discuss: Introduction (00:00) Simon’s Background and Journey into Nutrition Science (01:26) The Importance of Science and Objectivity in Nutrition Advice (08:38) Barriers to Healthy Eating and Population-Level Solutions (16:06) Challenges of Adopting Plant-Based Diets and Solutions (30:38) Omega-3 Fatty Acids: Health Benefits and Plant-Based Sources (38:17) Conclusion and Final Thoughts on Nutrition and Health (47:21) This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Episode #329. Boost metabolic health and prevent disease with expert insights from an all-star lineup of scientists. Learn key strategies for improving metabolic health, including metabolic flexibility, muscle health, and the critical roles of diet and exercise in preventing type 2 diabetes and fatty liver disease. In this episode, you’ll hear from a distinguished panel of specialists including applied exercise physiologist Inigo San Millan, PhD; skeletal muscle expert Don Layman, PhD; type 2 diabetes authority Roy Taylor, PhD; dietitian and researcher Andrea Glenn, PhD, RD; nutrition scientist Alan Flanagan, PhD; nutrition scientist and endocrinologist Christos Mantzoros MD, DSc, PhD; and physician and researcher Richard Johnson, MD. Specifically, we discuss: Intro (00:00) What is Metabolic Health (01:35) Metabolic Health, Mitochondria, Defining 'Metabolise', Metabolic Flexibility (07:02) The Importance of Skeletal Muscle for Metabolic Health (20:03) Exercise for metabolic health ****Zone 2 (28:36) Twin Cycle Hypothesis (56:45) Understanding the Personal Fat Threshold (01:08:15) Summary of the DiRECT Trial: Examining the Twin Cycle Hypothesis with Roy Taylor (01:17:08) Are DASH, Nordic, Mediterranean, and Portfolio diets good for preventing and managing diabetes? (01:36:46) Understanding Non-Alcoholic Fatty Liver Disease and Its Development (01:42:39) The Science of Hepatic Fat Oxidation (01:49:37) Consequences and Effects of Fatty Liver Disease (01:55:14) Linking Non-Alcoholic Fatty Liver Disease with Type 2 Diabetes (02:00:42) Combination of Fructose and Saturated fat on Metabolic Health (02:13:21) Type of fat and its effect on Metabolic Health (02:17:35) What cause Metabolic Health: fat or fructose (02:24:01) New Fat Storage Mechanisms - Personal Fat Threshold (02:27:50) Modern Techniques for Accurate Body Fat Measurement (02:31:52) Health metabolic biomarkers (02:36:51) Ectopic fat (02:38:19) Fat storage and metabolic health (02:39:10) Evolutionary Insights into Human Fat Storage (02:42:02) Fatty Liver Disease (02:45:46) Outro (2:57:46) Connect with today’s guests and listen to their previous episodes at the links above. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high-protein Plant Performance recipe book

Episode #328. Are eggs a superfood or a ticking time bomb? The answer is in your genes. Join me to unpack the surprising science of how eggs affect your health depending on your genetic makeup, helping you understand if they’re safe for you. Discover the two tests you can take to find out if you’re among the 30% of people who are cholesterol hyper-absorbers. You’ll also learn the difference between dietary and blood cholesterol, why cholesterol absorption varies, and what steps to take based on your test results. Specifically, we discuss: Introduction: Are Eggs Superfoods or Cholesterol Bombs? (00:00) Understanding Cholesterol: Dietary vs. Blood Levels (01:25) The Genetic Factors Influencing Cholesterol Absorption (04:31) Identifying Cholesterol Hyperabsorbers: Are You One? (09:20) Testing Methods for Cholesterol Sensitivity (12:41) Dietary Tips for Cholesterol Hyperabsorbers (13:59) Key Insights: 5 Critical Facts About Eggs and Heart Health (18:06) Concluding Thoughts (21:23) Head to the full show notes for supporting studies and phytosterol testing options. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Shopify Shopify, the world's leading e-commerce platform, helps you turn browsers into buyers with the internet’s best-converting check out–up to 36% better compared to other leading e-commerce platforms. To boost your conversion rate, and grow your business, sign up for a one-dollar-per-month trial period at shopify.com/proof. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Episode #327. Butter, bone broth, and eating like our ancestors: join me on The Ellen Fisher Podcast to bust some prolific nutrition myths. Tune in to unpack my core nutrition philosophy, evaluate how popular diets can impact your health, and examine some key foods that are either idolised as superfoods or condemned as dangerous. If you have questions about keto, carnivore, antinutrients, or other hot nutrition topics, this episode is for you. Specifically, we discuss: Introduction (00:00) Exploring Personal Nutritional Philosophy (02:31) Science's Role in Nutritional Understanding (06:33) Integrating Science and Nature in Dietary Patterns (10:55) Ancestral Diets Explained (14:40) Saturated Fats and ApoB: Their Crucial Role in Diet (21:03) Strategies for Reducing Saturated Fat and ApoB Levels (26:49) Analyzing Evidence Against Saturated Fat Claims (30:16) Polyunsaturated Fats: Health Impacts Unveiled (40:13) Processed Foods and Overconsumption Risks (47:33) Butter and Saturated Fats: Revealing the True Health Effects (49:26) Comparative Analysis of Various Diets and Health Outcomes (53:30) Debunking Anti-Nutrient Myths (01:04:36) Debating Contrasting Nutritional Perspectives with Paul Saladino (01:16:07) Saturated Fats Comparison: Coconut vs. Red Meat (01:22:26) The Importance of Personal Health Metrics (01:25:15) Evaluating Plant Milks and Processed Food Alternatives (01:29:26) Beef Liver Consumption and Nutrient Toxicity Risks (01:31:15) Critiquing Vegan Diets and Low-Fat Diet Misconceptions (01:36:54) Holistic Health and Longevity: Defining the Ultimate Goal (01:45:32) Conclusion and Key Takeaways (01:48:07) Discover more of the Ellen Fisher podcast at https://www.ellenfisher.com/podcast, or listen to her previous appearance on The Proof. Visit the full show notes for more insights and supporting studies. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. LMNT Stay hydrated with LMNT - a meaningful dose of electrolytes in a science-backed ratio. Receive a free LMNT sample pack with any order when you purchase via drinklmnt.com/simon. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book

Episode #326. Could the oils you’re using in the kitchen be increasing your risk of chronic disease? Explore the essential facts about dietary fats and how they affect your health markers in this focused deep dive. Learn which oils to eat and avoid, how to adjust your diet for optimal intake, and how fats can make the difference between health and chronic disease. Specifically, I cover: Introduction to Dietary Fats (00:00) Types of Fats Explained (02:27) Essential vs. Non-Essential Fats - What's the Difference? (07:54) Fats and Cardiovascular Health - Unveiling the Connection (10:32) How Dietary Fats Influence Blood Pressure (17:47) The Fat-Inflammation Link (20:29) Exploring the Relationship Between Fats and Insulin Resistance (26:03) Long-Term Health Outcomes of Dietary Fat Consumption (29:51) Optimising Fat Intake: Practical Dietary Recommendations (36:22) Wrapping up and Final Thoughts (41:25) Head to the full show notes for additional resources and supporting studies. This episode is brought to you by: 38TERA Consider 38TERA's DMN-01 prebiotic supplement a daily multivitamin for your gut. Formulated by yours truly and gastroenterologist Dr Will Bulsiewicz. Use code THEPROOF for a discount at checkout. Eimele Eimele Essential 8 is a comprehensive multivitamin that is scientifically formulated to complement your plant-rich diet, increase and sustain your energy, and support the immune system, as well as heart and brain health. Head to Eimele.com and use code SIMON at checkout for 10% off your first order. WHOOP Whoop, the most advanced fitness and health wearable available. Your personalised fitness and health coach to recover faster, sleep better, and train smarter. Claim your first month free on join.whoop.com/simon. Momentous My go-to supplement brand for protein and creatine is Momentous. Get 36% off subscriptions, and 20% off one-off purchases, by using the code LIVINGPROOF at checkout at livemomentous.com. Want to support the show? The best way to support the show is to use the products and services offered by our sponsors. To check them out, and enjoy great savings, visit theproof.com/friends. You can also show your support by leaving a review on the Apple Podcast app and/or sharing your favourite episodes with your friends and family. Simon Hill, MSc, BSc (Hons) Creator of theproof.com and host of The Proof with Simon Hill Author of The Proof is in the Plants Watch the episodes on YouTube or listen on Apple/Spotify Connect with me on Instagram, Twitter, and Facebook Nourish your gut with my Plant-Based Ferments Guide Download my complimentary Two-Week Meal Plan and high protein Plant Performance recipe book